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Stochastic Simulations of the ErbB Signaling Pathways Demonstrate the Importance of Spatial Organization in Signal Transduction
Fig. 3. Computed cytosolic temporal profiles
Cytosolic temporal profiles computed using the coupled-spatial nonspatial simulation algorithm (CSNSA) or the ordinary differential equations (ODE) model. The temporal profiles of total Grb2 (top left), total PLCg (top right), total pShc (bottom left), and total Sos (bottom right) are shown for each domain and the CSNSA is compared with the ODE.
Credits: Michelle Costa, University of New Mexico
