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Stochastic Modeling and Simulation of Cell Polarization During Mating in Budding Yeast
Polarisome Fragmentation and Scanning
Earlier work by Yi demonstrated polarisome fragmentation and scanning. (A) Spa2-GFP cells treated with LatA show multiple polarisomes (top). Washing away the LatA collapses the polarisome fragments into a single structure (bottom) (B) Spa2-mCherry (red) can be seen scanning along the polarized front edge dened by Ste20-GFP in a low-factor gradient. Scale bar = 10 m.
Credits: Tau-Mu Yi, Department of Developmental Cell Biology, University of California, Irvine