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www.CHOgenome.org

Projects:
IGERT: Systems Biology of Cells in Engineered...
Institution:
University of Delaware
Primary Strategic Goal:
Research Infrastructure: Build the Nation's research capability through critical investments in advanced instrumentation, facilities, cyber infrastructure, and experimental tools.
Secondary Strategic Goal:
Discovery: Foster research that will advance the frontiers of knowledge, emphasizing areas of greatest opportunity and potential benefit and establishing the Nation as a global leader in fundamental transformational science and engineering.

Achievement/Results

Prof. Kelvin Lee’s group at the University of Delaware recently reported the creation of an international industrial-academic-government partnership to host, maintain, and disseminate genome-scale information on Chinese hamster ovary cells… the most important platform cell line used in the production of over $60 billion dollars of biopharmaceuticals each year in the United States (reported in Hammond S, Kaplarevic M, Borth N, Betenbaugh M, Lee KH (2012). Chinese Hamster Genome Database: An Online Resource for the CHO Community at www.CHOgenome.org, Biotechnology and Bioengineering 109: 1353-1356). This work was supported by NSF.

Address Goals

This work brings together the international community working with CHO cells to advance shared information and resources related to genome-scale data through a common infrastructure. Having a reference genome provides an opportunity for design of new cell lines and more efficient and effective manufacturing of medicines.

Posted By:
Kelvin Lee
Posted:
December 2, 2013