Achievement

IGERT student Ryan Sartor is currently involved with a project in the lab of Steve Briggs that aims to create a protein atlas for Zea mays. This is a collection of semi-quantitative proteome profiles from different tissues at different times of development and also under several abiotic and biotic stress conditions. For each sample, both unmodified and phosphorylated proteins are examined. With tools and knowledge gained through interaction with the Bandeira lab, Ryan has taken up a project to analyze phosphorylation events that occur in a well characterized region of the kinase domain called the activation loop. Phosphorylation of this region is thought to be highly related to the activation of many kinases. Ryan is using a correlation-based analysis in an attempt to identify possible targets of these "activated" kinases.