Achievement
Studies on PET imaging and tracers
Project
IGERT: Returning the Radio to Chemistry: Integrating Radiochemistry into a Chemistry Ph.D. Program
University
City University of New York Hunter College
(New York, NY)
PI
Research Achievements
Studies on PET imaging and tracers
- Optimized the chemistry of radiolabeling an aptamer with the PET tracer zirconium-89 and characterized in vitro properties. This is the first aptamer for in vivo PET imaging
- We completed PET imaging and biodistribution studies of a radiolabeled monoclonal antibody specific for pancreatic ductal adenocarcinoma (PDAC).
- We developed a new method for radiolabeling targeting entities with the PET tracer fluorine-18 that will be applicable for many applications. It is a rapid and highly sufficient method, which is currently being optimized with "green" chemistry considerations. This is a highly exciting project since it will be of considerable use for the research community as well as for possible clinical applications.
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